EXENDIN-(9-39) CORRECTS FASTING HYPOGLYCEMIA IN SUR-1 MICE BY LOWERING cAMP IN PANCREATIC ß-CELLS AND INHIBITING INSULIN SECRETION

From the Division of Endocrinology, Department of Pediatrics, The Children’s Hospital of Philadelphia, 3615 Civic Center Boulevard, Philadelphia, Pennsylvania, Institute of Diabetes, Obesity and Metabolism, University of Pennsylvania, Philadelphia, Pennsylvania, and Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Pennsylvania, 415 Curie Boulevard, Philadelphia, Pennsylvania Running Title: Effect of Exendin-(9-39) in SUR-1 mice Address correspondence to: Doris A. Stoffers, MD, PhD, Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Pennsylvania School of Medicine, Clinical Research Building 611 B, 415 Curie Boulevard, Philadelphia, Pennsylvania 19104, Office telephone: (215) 5735413, Office fax: (215)898-5408, email: [email protected], or Diva D. De León, MD, Division of Endocrinology/Diabetes, Department of Pediatrics, The Children’s Hospital of Philadelphia, 3615 Civic Center Boulevard, Philadelphia, Pennsylvania 19104, Office telephone: (215)590-3420 Office fax: (215)590-1605, email: [email protected].